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Article

Identifying novel polymorphisms in the canine tryptophan hydroxylase 2 gene.

The Journal of veterinary medical science - 1 Oct 2008

Kaneko Fumihiro, Masuda Koji, Takeuchi Yukari, Mori Yuji

Abstract excerpt

Tryptophan hydroxylase (TPH) serves as the rate-limiting enzyme in the biosynthesis of serotonin, and two forms of TPH genes, TPH1 and TPH2, have been reported with specific nucleotide sequences and expression patterns. We determined the sequences of these two genes and identified polymorphisms within their coding regions. We identified five novel single nucleotide polymorphisms in the TPH2 gene, one of which...

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Source

Identifiers

PMID: 18981671
DOI: 10.1292/jvms.70.1117

Genes

TPH2
TPH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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