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Article

Intranasal delivery of influenza subunit vaccine formulated with GEM particles as an adjuvant.

The AAPS journal - 1 Jun 2010

Saluja Vinay, Amorij Jean P, van Roosmalen Maarten L, Leenhouts Kees, Huckriede Anke, Hinrichs Wouter L J, Frijlink Henderik W

Abstract excerpt

Nasal administration of influenza vaccine has the potential to facilitate influenza control and prevention. However, when administered intranasally (i.n.), commercially available inactivated vaccines only generate systemic and mucosal immune responses if strong adjuvants are used, which are often...

Read the complete abstract on PubMed

Topics

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Share to Adjuvants, Immunologic
Share to Administration, Intranasal
Share to Chemistry, Pharmaceutical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemagglutination Inhibition Tests

Share to Influenza Vaccines

Share to Injections, Intramuscular

Share to Lactococcus lactis

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Source

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Identifiers

PMID: 20058113
DOI: 10.1208/s12248-009-9168-2
PMCID: PMC2844513

Genes

GEM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20058113-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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