Article
Reduced sox9 function promotes heart valve calcification phenotypes in vivo.
Circulation research - 5 Mar 2010
Peacock Jacqueline D, Levay Agata K, Gillaspie Devin B, Tao Ge, Lincoln Joy
Abstract excerpt
RATIONALE: Calcification of heart valve structures is the most common form of valvular disease and is characterized by the appearance of bone-like phenotypes within affected structures. Despite the clinical significance, the underlying etiology of disease onset and progression is largely unknown...
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