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Article

Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos

22 Apr 2004

Abstract excerpt

Abnormalities in valvuloseptal development significantly contribute to congenital heart defects, yet the underlying causes are complex and poorly understood. Early cardiac regulatory genes are differentially expressed during valvuloseptal development, consistent with novel functions during heart chamber formation in chicken and mouse embryos. Distinct valve cell lineages were identified in the leaflets, chordae...

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Identifiers

PMID: 15162503
DOI: 10.1002/dvdy.20051

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Source receipt: pubmed, retrieved 7 Sept 2026.

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