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Article

Gene methylation in breast ductal fluid from BRCA1 and BRCA2 mutation carriers.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2010

Antill Yoland C, Mitchell Gillian, Johnson Sandra A, Devereux Lisa, Milner Alvin, Di Iulio Juliana, Lindeman Geoffrey J, Kirk Judy, Phillips Kelly Anne, Campbell Ian G

Abstract excerpt

PURPOSE: Genomic alterations (including gene hypermethylation) are likely to precede the phenotypic changes associated with breast tumorigenesis. From a prospective collection of ductal lavage (DL) samples from women with a known mutation in BRCA1 or BRCA2, we have assessed promoter methylation with a comparison of results with several variables, including breast cancer (BC) outcome. EXPERIMENTAL DESIGN:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20056647
DOI: 10.1158/1055-9965.EPI-09-0359

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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