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Article

Assessing the stability of Alzheimer's amyloid protofibrils using molecular dynamics.

The journal of physical chemistry. B - 4 Feb 2010

Lemkul Justin A, Bevan David R

Abstract excerpt

Amyloid fibrils represent a stable form of many misfolded proteins associated with numerous diseases. Among these are Parkinson's disease (alpha-synuclein), Type II diabetes (islet amyloid polypeptide), and Alzheimer's disease (amyloid beta-peptide, Abeta). The appearance of Abeta fibrils in neural tissue is a hallmark of Alzheimer's disease, and many studies have been conducted to determine and analyze the...

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Identifiers

PMID: 20055378
DOI: 10.1021/jp9110794

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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