Article
Evaluating the association of FAAH common gene variation with childhood, adult severe obesity and type 2 diabetes in the French population.
Obesity facts - 1 Jan 2008
Durand Emmanuelle, Lecoeur Cécile, Delplanque Jérôme, Benzinou Michael, Degraeve Franck, Boutin Philippe, Marre Michel, Balkau Beverley, Charpentier Guillaume, Froguel Philippe, Meyre David
Abstract excerpt
OBJECTIVE: The endocannabinoid pathway is involved in eating behavior and body weight regulation in both animals and humans. The association of a missense polymorphism (Pro129Thr) in FAAH gene with overweight/obesity has been recently questioned. SUBJECTS AND METHODS: To evaluate the contribution of the FAAH gene variation in polygenic obesity and type 2 diabetes mellitus (T2DM) in the French population, we...
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