Article
The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites.
Journal of molecular medicine (Berlin, Germany) - 1 May 2007
Jensen Dorit P, Andreasen Camilla H, Andersen Mette K, Hansen Lars, Eiberg Hans, Borch-Johnsen Knut, Jørgensen Torben, Hansen Torben, Pedersen Oluf
Abstract excerpt
Food intake and weight gain are influenced by endocannabinoids whose actions are regulated by the fatty acid amide hydrolase (FAAH) enzyme. The homozygous Thr/Thr genotype of the functional Pro129Thr variant (rs324420) in the gene encoding FAAH was recently reported to associate with overweight and obesity in white and black populations. We investigated the Pro129Thr variant in relation to overweight and obesity...
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