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Article

High-fat, carbohydrate-free diet markedly aggravates obesity but prevents beta-cell loss and diabetes in the obese, diabetes-susceptible db/db strain.

Obesity facts - 1 Jan 2008

Mirhashemi Farshad, Kluth Oliver, Scherneck Stephan, Vogel Heike, Kluge Reinhart, Schurmann Annette, Joost Hans-Georg, Neschen Susanne

Abstract excerpt

OBJECTIVE: We have previously reported that a high-fat, carbohydrate-free diet prevents diabetes and beta-cell destruction in the New Zealand Obese (NZO) mouse strain. Here we investigated the effect of diets with and without carbohydrates on obesity and development of beta-cell failure in a seco...

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Identifiers

PMID: 20054191
DOI: 10.1159/000176064
PMCID: PMC6452171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20054191-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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