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Article

Diet-genotype interactions in the early development of obesity and insulin resistance in mice with a genetic deficiency in tumor necrosis factor-alpha.

Metabolism: clinical and experimental - 1 Jul 2010

Bouter Brenda, Geary Nori, Langhans Wolfgang, Asarian Lori

Abstract excerpt

The onset of insulin resistance, the sites of action, and the mechanisms through which tumor necrosis factor-alpha (TNF-alpha) exacerbates the increase in adiposity and the development of insulin resistance in mice fed high-fat (HF) diet remain unclear. Here we investigated the effect of TNF-alph...

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Identifiers

PMID: 20045154
DOI: 10.1016/j.metabol.2009.11.003

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20045154-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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