Article
The choice of cell fate in the epidermis of Drosophila.
Cell - 22 Mar 1991
Heitzler P, Simpson P
Abstract excerpt
In Drosophila, neural precursors are formed in a spaced pattern separated by intervening epidermal cells. Segregation of neural and epidermal lineages relies on cellular interactions. Failure of this cell communication, as in the mutants Notch (N), Delta, and shaggy, results in most or all of the cells becoming neural. Cells mutant for N and shaggy, but not Delta, autonomously adopt the neural fate when adjacent...
Topics
- Animals
- Cell Differentiation
- Drosophila
- Epidermal Cells
- Epidermis
- Genes
- Mutation
- Neurons
- Stem Cells