Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate.

Current biology : CB - 13 Nov 2001

Ramain P, Khechumian K, Seugnet L, Arbogast N, Ackermann C, Heitzler P

Abstract excerpt

BACKGROUND: The Notch receptor triggers a wide range of cell fate choices in higher organisms. In Drosophila, segregation of neural from epidermal lineages results from competition among equivalent cells. These cells express achaete/scute genes, which confer neural potential. During lateral inhibition, a single neural precursor is selected, and neighboring cells are forced to adopt an epidermal fate. Lateral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Dishevelled Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glycogen Synthase Kinase 3

Share to Insect Proteins

Share to Phosphoproteins

Share to Receptors, Notch

Share to Stem Cells

Share to Wnt1 Protein

Source

Identifiers

PMID: 11719214
DOI: 10.1016/s0960-9822(01)00562-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate.PMID 11719214Read ↗

The first deltex null mutant indicates tissue-specific deltex-dependent Notch signaling in Drosophila.Semantic proximity Read ↗

Genetic control of dorsoventral patterning and neuroblast specification in the Drosophila Central Nervous System.Semantic proximity Read ↗

Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila.Semantic proximity Read ↗

A Notch-independent function of Suppressor of Hairless during the development of the bristle sensory organ precursor cell of Drosophila.Semantic proximity Read ↗

Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements.Semantic proximity Read ↗

Lateral inhibition in proneural clusters: cis-regulatory logic and default repression by Suppressor of Hairless.Semantic proximity Read ↗

Evidence for the involvement of dominant-negative Notch molecules in the normal course of Drosophila development.Semantic proximity Read ↗

deltex, a locus interacting with the neurogenic genes, Notch, Delta and mastermind in Drosophila melanogaster.Semantic proximity Read ↗

Genetic characterization of the Drosophila melanogaster Suppressor of deltex gene: A regulator of notch signaling.Semantic proximity Read ↗

A genetic screen for novel components of the notch signaling pathway during Drosophila bristle development.Semantic proximity Read ↗

Drosophila Notch receptor activity suppresses Hairless function during adult external sensory organ development.Semantic proximity Read ↗

Inhibition of cell fate in Drosophila by Enhancer of split genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.