Article
Regulation of proneural gene expression and cell fate during neuroblast segregation in the Drosophila embryo.
Development (Cambridge, England) - 1 Apr 1992
Skeath J B, Carroll S B
Abstract excerpt
The Drosophila embryonic central nervous system develops from sets of progenitor neuroblasts which segregate from the neuroectoderm during early embryogenesis. Cells within this region can follow either the neural or epidermal developmental pathway, a decision guided by two opposing classes of genes. The proneural genes, including the members of the achaete-scute complex (AS-C), promote neurogenesis, while the...
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