Article
The interleukin 1 beta (IL1B) gene is associated with failure to achieve remission and impaired emotion processing in major depression.
Biological psychiatry - 15 Mar 2010
Baune Bernhard T, Dannlowski Udo, Domschke Katharina, Janssen Debbie G A, Jordan Margaret A, Ohrmann Patricia, Bauer Jochen, Biros Erik, Arolt Volker, Kugel Harald, Baxter Alan G, Suslow Thomas
Abstract excerpt
BACKGROUND: Accumulating evidence suggests the involvement of inflammatory processes and cytokines in particular in the pathophysiology of major depression (MDD) and resistance to antidepressant treatment. Furthermore, amygdala and anterior cingulate cortex (ACC) responsiveness to emotional stimu...
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