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Article

A preliminary investigation of the influence of CREB1 gene on treatment resistance in major depression.

Journal of affective disorders - 1 Jan 2011

Serretti Alessandro, Chiesa Alberto, Calati Raffaella, Massat Isabelle, Linotte Sylvie, Kasper Siegfried, Lecrubier Yves, Antonijevic Irina, Forray Carlos, Snyder Lenore, Bollen Joseph, Zohar Joseph, De Ronchi Diana, Souery Daniel, Mendlewicz Julien

Abstract excerpt

BACKGROUND: The transcription factor Cyclic adenosine monophosphate Response Element Binding (CREB) protein has been repeatedly involved in the aetiology and pharmacotherapy of major depression (MD). The aim of this study was to investigate the potential association of a set of single nucleotide polymorphisms (SNPs) in CREB1 gene and both MD and response, remission and treatment resistance to antidepressants....

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Identifiers

PMID: 20643483
DOI: 10.1016/j.jad.2010.06.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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