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Article

Effect of mutations in the human immunodeficiency virus type 1 protease on cleavage of the gp41 cytoplasmic tail.

Journal of virology - 1 Mar 2010

Waheed Abdul A, Ablan Sherimay D, Sowder Raymond C, Roser James D, Schaffner Carl P, Chertova Elena, Freed Eric O

Abstract excerpt

We previously reported that human immunodeficiency virus type 1 (HIV-1) develops resistance to the cholesterol-binding compound amphotericin B methyl ester (AME) by acquiring mutations (P203L and S205L) in the cytoplasmic tail of the transmembrane envelope glycoprotein gp41 that create cleavage s...

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Identifiers

PMID: 20042499
DOI: 10.1128/JVI.02002-09
PMCID: PMC2826043

Genes

PIR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20042499-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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