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Article

The cytoplasmic domain of human immunodeficiency virus type 1 transmembrane protein gp41 harbors lipid raft association determinants.

Journal of virology - 1 Jan 2010

Yang Polung, Ai Li-Shuang, Huang Shu-Chen, Li Hsiao-Fen, Chan Woan-Eng, Chang Chih-Wei, Ko Chiung-Yuan, Chen Steve S-L

Abstract excerpt

The molecular basis for localization of the human immunodeficiency virus type 1 envelope glycoprotein (Env) in detergent-resistant membranes (DRMs), also called lipid rafts, still remains unclear. The C-terminal cytoplasmic tail of gp41 contains three membrane-interacting, amphipathic alpha-helical sequences, termed lentivirus lytic peptide 2 (LLP-2), LLP-3, and LLP-1, in that order. Here we identify determinants...

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Identifiers

PMID: 19793805
DOI: 10.1128/JVI.00899-09
PMCID: PMC2798425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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