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Article

Accelerated evolution of SIV env within the cerebral compartment in the setting of morphine-dependent rapid disease progression.

Virology - 15 Mar 2010

Rivera-Amill Vanessa, Noel Richard J, García Yashira, Rivera Ivelisse, Iszard Marcus, Buch Shilpa, Kumar Anil

Abstract excerpt

Human immunodeficiency virus-1 (HIV-1) and simian immunodeficiency virus (SIV) have been shown to compartmentalize within various tissues, including the brain. However, the evolution of viral quasispecies in the setting of drug abuse has not been characterized. The goal of this study was to examine viral evolution in the cerebral compartment of morphine-dependent and control macaques to determine its role in...

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Identifiers

PMID: 20042209
DOI: 10.1016/j.virol.2009.11.046
PMCID: PMC2828616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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