Article
SIV Vpr evolution is inversely related to disease progression in a morphine-dependent rhesus macaque model of AIDS.
Virology - 15 Mar 2007
Noel Richard J, Kumar Anil
Abstract excerpt
Three of six morphine-dependent monkeys progressed rapidly to AIDS and died by 20 weeks in our SIV/SHIV non-human primate model of drug addiction and AIDS. We studied the evolution of the SIV vpr gene in both cerebrospinal fluid (CSF) and plasma in these rapid progressors, in their normal progres...
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