Article
Adaptive evolution of simian immunodeficiency viruses isolated from 2 conventional-progressor macaques with encephalitis.
The Journal of infectious diseases - 15 Jun 2008
Dang Que, Goeken Robert M, Brown Charles R, Plishka Ronald J, Buckler-White Alicia, Byrum Russell, Foley Brian T, Hirsch Vanessa M
Abstract excerpt
Simian immunodeficiency virus-infected macaques may develop encephalitis, a feature more commonly observed in macaques with rapid progressive disease than in those with conventional disease. In this report, an analysis of 2 conventional progressors with encephalitis is described. Phylogenetic analyses of viruses isolated from the cerebrospinal fluid and plasma of both macaques demonstrated compartmentalization....
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