Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of tau kinases (CDK5R1 and GSK3B) in Parkinson's disease: a study from India.

Neurobiology of aging - 1 Jul 2012

Das Gautami, Misra Amar K, Das Shyamal K, Ray Kunal, Ray Jharna

Abstract excerpt

Glycogen synthase kinase-3β (GSK3B) and cyclin-dependent kinase 5 (CDK5) are the 2 major protein kinases involved in abnormal phosphorylation of tau. To determine their potential role in the pathogenesis of Parkinson's disease (PD) we analyzed 2 functional single nucleotide polymorphisms (SNPs) of GSK3B (rs334558 and rs6438552) and rs735555 of CDK5 regulatory subunit 1 (CDK5R1) in 373 PD cases and 346 healthy...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to Glycogen Synthase Kinase 3
Share to Glycogen Synthase Kinase 3 beta
Share to India
Share to Nerve Tissue Proteins
Share to Parkinson Disease
Share to Risk Factors
Share to tau Proteins

Source

Identifiers

PMID: 21130530
DOI: 10.1016/j.neurobiolaging.2010.10.016

Genes

CDK5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of tau kinases (CDK5R1 and GSK3B) in Parkinson's disease: a study from India.PMID 21130530Read ↗

The association between glycogen synthase kinase 3 beta polymorphisms and Parkinson's disease susceptibility: a meta-analysis.Semantic proximity Read ↗

GSK3β reduces risk of sporadic Parkinson's disease in ethnic Chinese.Semantic proximity Read ↗

Common Polymorphisms in the GSK3β Gene May Contribute to the Pathogenesis of Alzheimer Disease: A Meta-Analysis.Semantic proximity Read ↗

Alzheimer's Disease-Associated SNP rs708727 in SLC41A1 May Increase Risk for Parkinson's Disease: Report from Enlarged Slovak Study.Semantic proximity Read ↗

APOE rs405509 polymorphism and Parkinson's disease risk in the Chinese population.Semantic proximity Read ↗

DJ-1 variants in Indian Parkinson's disease patients.Semantic proximity Read ↗

GSK3B polymorphisms alter transcription and splicing in Parkinson's disease.Semantic proximity Read ↗

SNCA, MAPT, and GSK3B in Parkinson disease: a gene-gene interaction study.Semantic proximity Read ↗

Genetic variation in the tau kinases pathway may modify the risk and age at onset of Alzheimer's disease.Semantic proximity Read ↗

Microtubule-associated protein tau (MAPT) influences the risk of Parkinson's disease among Indians.Semantic proximity Read ↗

Mini-review: Role of the PI3K/Akt pathway and tyrosine phosphatases in Alzheimer's disease susceptibility.Semantic proximity Read ↗

Genetic variants of GSK3B are associated with biomarkers for Alzheimer's disease and cognitive function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.