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Article

Evaluation of SNPs associated with mammographic density in European women with mammographic density in Asian women from South-East Asia.

Breast cancer research and treatment - 1 Sept 2023

Mariapun Shivaani, Ho Weang Kee, Eriksson Mikael, Tai Mei Chee, Mohd Taib Nur Aishah, Yip Cheng Har, Rahmat Kartini, Li Jingmei, Hartman Mikael, Hall Per, Easton Douglas F, Lindstrom Sara, Teo Soo-Hwang

Abstract excerpt

PURPOSE: Mammographic density (MD), after accounting for age and body mass index (BMI), is a strong heritable risk factor for breast cancer. Genome-wide association studies (GWAS) have identified 64 SNPs in 55 independent loci associated with MD in women of European ancestry. Their associations with MD in Asian women, however, are largely unknown. METHOD: Using linear regression adjusting for age, BMI, and...

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Identifiers

PMID: 37338730
DOI: 10.1007/s10549-023-06984-2
PMCID: PMC10865780

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