Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease.

The Journal of clinical investigation - 1 Jan 2010

Matkovich Scot J, Van Booven Derek J, Hindes Anna, Kang Min Young, Druley Todd E, Vallania Francesco L M, Mitra Robi D, Reilly Muredach P, Cappola Thomas P, Dorn Gerald W

Abstract excerpt

Sporadic heart failure is thought to have a genetic component, but the contributing genetic events are poorly defined. Here, we used ultra-high-throughput resequencing of pooled DNAs to identify SNPs in 4 biologically relevant cardiac signaling genes, and then examined the association between all...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Black People
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heat-Shock Proteins

Share to HSP27 Heat-Shock Proteins

Share to Molecular Chaperones

Share to Sequence Analysis, DNA

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 20038796
DOI: 10.1172/JCI39085
PMCID: PMC2798680

Genes

HSPB7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20038796-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease.PMID 20038796Read ↗

Genetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy.Semantic proximity Read ↗

A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy.Semantic proximity Read ↗

The genomic architecture of sporadic heart failure.Semantic proximity Read ↗

Common variants in HSPB7 and FRMD4B associated with advanced heart failure.Semantic proximity Read ↗

Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy.Semantic proximity Read ↗

A DNA resequencing array for pathogenic mutation detection in hypertrophic cardiomyopathy.Semantic proximity Read ↗

Targeted analysis of whole genome sequence data to diagnose genetic cardiomyopathy.Semantic proximity Read ↗

Rare Variants in Cardiomyopathy Genes Associated With Stress-Induced Cardiomyopathy.Semantic proximity Read ↗

Association of an intronic, but not any exonic, FRMD4B sequence variant and heart failure.Semantic proximity Read ↗

Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure.Semantic proximity Read ↗

Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy.Semantic proximity Read ↗

Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.