Article
Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy.
Scientific reports - 15 May 2018
Lacey Cameron J, Doudney Kit, Bridgman Paul G, George Peter M, Mulder Roger T, Zarifeh Julie J, Kimber Bridget, Cadzow Murray J, Black Michael A, Merriman Tony R, Lehnert Klaus, Bickley Vivienne M, Pearson John F, Cameron Vicky A, Kennedy Martin A
Abstract excerpt
The pathophysiology of stress cardiomyopathy (SCM), also known as takotsubo syndrome, is poorly understood. SCM usually occurs sporadically, often in association with a stressful event, but clusters of cases are reported after major natural disasters. There is some evidence that this is a familial condition. We have examined three possible models for an underlying genetic predisposition to SCM. Our primary study...
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