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Article

Association of an intronic, but not any exonic, FRMD4B sequence variant and heart failure.

Clinical and translational science - 1 Aug 2010

Matkovich Scot J, Van Booven Derek J, Cappola Thomas P, Dorn Gerald W

Abstract excerpt

Common forms of heart failure (HF) exhibit familial clustering, but specific genetic risk factors have been challenging to identify. A recent single-nucleotide polymorphism (SNP) microarray study implicated a locus within an intron of FRMD4B in Caucasian HF. Here, we used next-generation resequencing of pooled DNA and individual Sequenom genotyping to test for associations between FRMD4B SNPs and ischemic and/or...

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Source

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Identifiers

PMID: 20718813
DOI: 10.1111/j.1752-8062.2010.00220.x
PMCID: PMC2925316

Genes

FRMD4B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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