Article
c.822+126T>G/C: a novel triallelic polymorphism of the TSSK6 gene associated with spermatogenic impairment in a Chinese population.
Asian journal of andrology - 1 Mar 2010
Su Dan, Zhang Wei, Yang Yuan, Zhang Hao, Liu Yun-Qiang, Bai Gang, Ma Yong-Xin, Peng Yan, Zhang Si-Zhong
Abstract excerpt
TSSK6 is a member of the testis-specific serine/threonine kinase family. Male Tssk6 knockout mice are infertile owing to spermatogenic impairment, including sperm count reduction, a decrease in motile sperm number and motility rates, and an increase in the number of sperms with abnormal morphology. We investigated the possible association between variations of the TSSK6 gene and spermatogenic impairment in...
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