Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Testis-specific serine/threonine kinase dTSSK2 regulates sperm motility and male fertility in Drosophila

7 May 2025

Abstract excerpt

Serine/threonine kinases of the TSSK (Testis-Specific Serine/Threonine Kinase) family play crucial roles in spermatogenesis and male fertility across species, but the underlying regulatory mechanism remains incompletely understood. In this study, we identified and characterized a novel TSSK homolog in Drosophila, named dTSSK2 (CG9222), which functions as the ortholog of human TSSK4. dTSSK2 is specifically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40335644
DOI: 10.1038/s42003-025-08163-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Testis-specific serine/threonine kinase dTSSK2 regulates sperm motility and male fertility in DrosophilaPMID 40335644Read ↗

Broad phosphorylation mediated by testis-specific serine/threonine kinases contributes to spermiogenesis and male fertilitySemantic proximity Read ↗

Tssk4 is essential for maintaining the structural integrity of sperm flagellumSemantic proximity Read ↗

Testis‐specific serine kinase 3 is required for sperm morphogenesis and male fertilitySemantic proximity Read ↗

Expression and localization of five members of the testis-specific serine kinase (Tssk) family in mouse and human sperm and testisSemantic proximity Read ↗

STK33 Phosphorylates Fibrous Sheath Protein AKAP3/4 to Regulate Sperm Flagella Assembly in SpermiogenesisSemantic proximity Read ↗

Tssk6 is essential for the regulation of male zebrafish fertilitySemantic proximity Read ↗

Sperm flagellar 2 (SPEF2) is essential for sperm flagellar assembly in humansSemantic proximity Read ↗

Identification of KIAA1210 as a novel X-chromosome-linked protein that localizes to the acrosome and associates with the ectoplasmic specialization in testesSemantic proximity Read ↗

Spem2, a novel testis-enriched gene, is required for spermiogenesis and fertilization in miceSemantic proximity Read ↗

Adenine nucleotide translocase 2 ( Ant2 ) is required for individualization of spermatogenesis of Drosophila melanogasterSemantic proximity Read ↗

Evolution of testis-specific kinases TSSK1B and TSSK2 in primates.Semantic proximity Read ↗

Disruption of TEX38 impairs sperm morphogenesis and the migration of sperm into the oviductSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.