Article
High frequency of somatic mutations in rat liver mitochondrial DNA.
Mutation research - 1 Mar 2010
Rotskaya Ulyana N, Rogozin Igor B, Vasyunina Elena A, Malyarchuk Boris A, Nevinsky Georgy A, Sinitsyna Olga I
Abstract excerpt
Somatic mutations in mitochondrial DNA (mtDNA) are thought to play an important role in both aging and neurodegenerative diseases although their specific contributions remain a subject of intense debate. We analyzed somatic mutations in the mtDNA control regions in the liver of Wistar rats. The m...
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