Article
A census of predicted mutational epitopes suitable for immunologic cancer control.
Human immunology - 1 Mar 2010
Warren René L, Holt Robert A
Abstract excerpt
The adaptive immune system can protect against spontaneously arising tumors, and the potential exists to reduce cancer incidence by priming adaptive immune responses with vaccines. Immunologic cancer control has been implemented for cancers caused by infectious agents, but not for spontaneous cancers caused by mutation. This is largely due to the high cost of preventative clinical trials and the lack of validated...
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