Article
KIR genotyping by multiplex PCR-SSP.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Kulkarni Smita, Martin Maureen P, Carrington Mary
Abstract excerpt
Diversity across KIR haplotypes stems from differences in numbers of inhibitory and activating receptors, as well as allelic polymorphism of individual genes. The KIR locus has undergone large expansions and contractions over time and is believed to be coevolving with genes encoding its HLA class I ligands located within the MHC locus. KIR and HLA compound genotypes have been associated with susceptibility to or...
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