Article
Facilitation of KIR genotyping by a PCR-SSP method that amplifies short DNA fragments.
Tissue antigens - 1 Nov 2007
Vilches C, Castaño J, Gómez-Lozano N, Estefanía E
Abstract excerpt
Detection of killer-cell immunoglobulin-like receptors (KIR) genes by polymerase chain reaction with sequence-specific primers (PCR-SSP) led in 1997 to the discovery that human genomes diverge largely in the KIR they encode. While only a few KIR genes are conserved in all humans, most individuals lack several those genes, which tend to associate in diverse haplotypic combinations. The PCR-SSP technique, updated...
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