Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oncogene-induced cellular senescence.

Advances in anatomic pathology - 1 Jan 2010

Chandeck Charlotte, Mooi Wolter J

Abstract excerpt

Oncogene-induced senescence (OIS) is a robust and sustained antiproliferative response brought about by oncogenic signaling resulting from an activating mutation of an oncogene, or the inactivation of a tumor-suppressor gene. The pathways mediating OIS are complex and incompletely elucidated but, the proliferative arrest involves activation of both the RB and p53 pathways. In addition, whereas there are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Cell Proliferation
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cellular Senescence

Share to Inflammation

Share to Neoplasms

Share to Nevus, Pigmented

Share to Oncogenes

Source

Identifiers

PMID: 20032638
DOI: 10.1097/PAP.0b013e3181c66f4e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oncogene-induced cellular senescence.PMID 20032638Read ↗

Oncogene-induced senescence: the bright and dark side of the response.Semantic proximity Read ↗

Oncogene‐induced senescence and melanoma: where do we stand?Semantic proximity Read ↗

Oncogene-Induced Cell Senescence — Halting on the Road to CancerSemantic proximity Read ↗

Cellular senescence: Its role in tumor suppression and agingSemantic proximity Read ↗

Cellular senescence: a double‐edged sword in the fight against cancerSemantic proximity Read ↗

The Senescent Side of Tumor SuppressionSemantic proximity Read ↗

Cellular Senescence in the Development and Treatment of CancerSemantic proximity Read ↗

Is Senescence Reversible?Semantic proximity Read ↗

Cellular senescence and cancerSemantic proximity Read ↗

Senescence As an Anticancer MechanismSemantic proximity Read ↗

Role of senescence induction in cancer treatmentSemantic proximity Read ↗

How Does Proliferative Homeostasis Change With Age? What Causes It and How Does It Contribute to Aging?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.