Oncogene‐induced senescence and melanoma: where do we stand?

Abstract excerpt

In recent years, many groups have detected biomarkers of cellular senescence in a plethora of neoplastic lesions, in model systems, and humans. Indeed, we have come to realize that oncogene-induced senescence (OIS) acts as a potent barrier to oncogenic transformation, operating alongside cell death programs. We have begun to uncover some of its underlying principles, but many fundamental questions remain. In this...

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• Share to Advanced biosensing and bioanalysis techniques
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