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Article

TCF7L2 rs7903146-macronutrient interaction in obese individuals' responses to a 10-wk randomized hypoenergetic diet.

The American journal of clinical nutrition - 1 Feb 2010

Grau Katrine, Cauchi Stephane, Holst Claus, Astrup Arne, Martinez J Alfredo, Saris Wim H M, Blaak Ellen E, Oppert Jean-Michel, Arner Peter, Rössner Stephan, Macdonald Ian A, Klimcakova Eva, Langin Dominique, Pedersen Oluf, Froguel Philippe, Sørensen Thorkild I A

Abstract excerpt

BACKGROUND: Transcription factor 7-like 2 (TCF7L2) rs7903146 associates with type 2 diabetes and may operate via impaired glucagon-like peptide 1 secretion, which is stimulated more by fat than by carbohydrate ingestion. OBJECTIVE: The objective was to examine the interaction between TCF7L2 rs7903146 and dietary fat and carbohydrate [high-fat, low-carbohydrate: 40-45% of energy as fat (HF); compared with low-fat,...

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Source

Identifiers

PMID: 20032493
DOI: 10.3945/ajcn.2009.27947

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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