Article
Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans.
International journal of obesity (2005) - 1 Nov 2009
Grau K, Hansen T, Holst C, Astrup A, Saris W H M, Arner P, Rössner S, Macdonald I, Polak J, Oppert J-M, Langin D, Martinez J A, Pedersen O, Sørensen T I A
Abstract excerpt
BACKGROUND: The A risk allele of rs9939609 of the fat mass- and obesity-associated gene (FTO) increases body fat mass. OBJECTIVE: To examine whether FTO rs9939609 affects obese individuals' response to a high-fat, low-carbohydrate (CHO) (HF) or low-fat, high-CHO (LF), hypo-energetic diet and whether the effect of the FTO variant depends on dietary fat and CHO content. DESIGN: In a 10-week, European, multi-centre...
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