Immunophenotypic features and t(14;18) (q32;q21) translocation of Chinese follicular lymphomas helps to distinguish subgroups.

doi:10.1186/1746-1596-8-154

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Immunophenotypic features and t(14;18) (q32;q21) translocation of Chinese follicular lymphomas helps to distinguish subgroups.

Diagnostic pathology - 18 Sept 2013

Zhang Fen, Yan Li-Xu, Lin Su-Xia, Ye Zi-Yin, Zhuang Heng-Guo, Yun Jing-Ping, Lin Han-Liang, Luo Dong-Lan, Xu Fang-Ping, Luo Xin-Lan, Cheng Jie, Zhang Ke-Ping, Liu Yan-Hui

Abstract excerpt

BACKGROUND: The revised 2008 World Health Organization classification maintains a histological grading system (grades 1-3) for follicular lymphoma (FL). The value of grading FL has been debated. This study will yield deeper insights into the morphologic, immunophenotypic characterization and t(14;18) translocation in FL and explore their significance of diagnosis of Chinese FL subgroups. METHODS: We...

Topics

Adult
Aged
Aged, 80 and over
Biomarkers, Tumor
China
Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 18
Diagnosis, Differential
Female
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Immunohistochemistry

Immunophenotyping

In Situ Hybridization, Fluorescence

Lymphoma, Follicular

Male

Middle Aged

Neoplasm Grading

Source

Open in PubMed Open full text

Identifiers

PMID: 24047469
DOI: 10.1186/1746-1596-8-154
PMCID: PMC3853627

Genes

BCL2
BCL6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunophenotypic features and t(14;18) (q32;q21) translocation of Chinese follicular lymphomas helps to distinguish subgroups.PMID 24047469Read ↗

Clinical features and prognosis analysis of patients with follicular lymphoma: A real-world study in ChinaSemantic proximity Read ↗

Low-grade follicular lymphoma with t(14;18) presents a homogeneous disease entity otherwise the rest comprises minor groups of heterogeneous disease entities with Bcl2 amplification, Bcl6 translocation or other gene aberrances.Semantic proximity Read ↗

The clinical and molecular taxonomy of t(14;18)-negative follicular lymphomas.Semantic proximity Read ↗

CD10-MUM1+ follicular lymphoma lacks BCL2 gene translocation and shows characteristic biologic and clinical features.Semantic proximity Read ↗

Navigating the Heterogeneity of Follicular Lymphoma and its Many Variants: An Updated Approach to Diagnosis and Classification.Semantic proximity Read ↗

The broad landscape of follicular lymphoma: Part I.Semantic proximity Read ↗

High-grade Follicular Lymphomas Exhibit Clinicopathologic, Cytogenetic, and Molecular Diversity Extending Beyond Grades 3A and 3B.Semantic proximity Read ↗

Follicular lymphoma and marginal zone lymphoma: how many diseases?Semantic proximity Read ↗

Molecular epidemiology of follicular lymphoma in Chinese: relationship with bcl-2/IgH translocation and bcl-6 397G/C polymorphism.Semantic proximity Read ↗

Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations.Semantic proximity Read ↗

BCL6-translocations affect the phenotype of follicular lymphomas only in the absence of t(14;18)IgH/BCL2.Semantic proximity Read ↗

Epidemiology of Follicular Lymphoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.