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Article

Establishment and characterization of a human gastrointestinal stromal tumour (GIST) xenograft in athymic nude mice.

Anticancer research - 1 Nov 2009

Revheim Mona-Elisabeth, Seierstad Therese, Berner Jeanne-Marie, Bruland Oyvind Sverre, Røe Kathrine, Ohnstad Hege Oma, Bjerkehagen Bodil, Bach-Gansmo Tore

Abstract excerpt

BACKGROUND: The majority of gastrointestinal stromal tumours (GISTs) contain oncogenic KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) or platelet-derived growth factor-alpha (PDGFRA) receptor tyrosine kinase (TK) mutations and are initially, but only temporarily sensitive to...

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Source

Identifiers

PMID: 20032375

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20032375-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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