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Article

[Establishment and pathologic analysis of imatinib-resistant gastrointestinal stromal tumor xenografts].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Mar 2012

Zheng Song, Wang Xiao-ju, Jia Jing, Pan Yue-long, Tao De-you, Lu Hong-sheng, Huang Ke-er

Abstract excerpt

OBJECTIVE: To establish and characterize imatinib-resistant gastrointestinal stromal tumor (GIST) xenografts. Further provided an ideal experimental platform through the imatinib-resistant GIST xenografts to investigate the mechanism of resistance to imatinib. METHODS: Imatinib-resistant GIST cells were injected under the skin of athymic nude mice to establish animal models of human imatinib-resistant GIST. The...

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Identifiers

PMID: 22800481
DOI: 10.3760/cma.j.issn.0529-5870.2012.03.007

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