Article
Longitudinal association of PCSK9 sequence variations with low-density lipoprotein cholesterol levels: the Coronary Artery Risk Development in Young Adults Study.
Circulation. Cardiovascular genetics - 1 Aug 2009
Huang Chiang-Ching, Fornage Myriam, Lloyd-Jones Donald M, Wei Gina S, Boerwinkle Eric, Liu Kiang
Abstract excerpt
BACKGROUND: Mutations of PCSK9 are associated cross-sectionally with plasma low-density lipoprotein cholesterol (LDL-C) levels, but little is known about their longitudinal association with LDL-C levels from young adulthood to middle age. METHODS AND RESULTS: We investigated the associations of 6...
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