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Article

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.

The New England journal of medicine - 23 Mar 2006

Cohen Jonathan C, Boerwinkle Eric, Mosley Thomas H, Hobbs Helen H

Abstract excerpt

BACKGROUND: A low plasma level of low-density lipoprotein (LDL) cholesterol is associated with reduced risk of coronary heart disease (CHD), but the effect of lifelong reductions in plasma LDL cholesterol is not known. We examined the effect of DNA-sequence variations that reduce plasma levels of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16554528
DOI: 10.1056/NEJMoa054013

Genes

PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16554528-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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