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Article

COL4A1 is associated with arterial stiffness by genome-wide association scan.

Circulation. Cardiovascular genetics - 1 Apr 2009

Tarasov Kirill V, Sanna Serena, Scuteri Angelo, Strait James B, Orrù Marco, Parsa Afshin, Lin Ping-I, Maschio Andrea, Lai Sandra, Piras Maria Grazia, Masala Marco, Tanaka Toshiko, Post Wendy, O'Connell Jeffrey R, Schlessinger David, Cao Antonio, Nagaraja Ramaiah, Mitchell Braxton D, Abecasis Gonçalo R, Shuldiner Alan R, Uda Manuela, Lakatta Edward G, Najjar Samer S

Abstract excerpt

BACKGROUND: Pulse wave velocity (PWV), a noninvasive index of central arterial stiffness, is a potent predictor of cardiovascular mortality and morbidity. Heritability and linkage studies have pointed toward a genetic component affecting PWV. We conducted a genome-wide association study to identi...

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Identifiers

PMID: 20031579
DOI: 10.1161/CIRCGENETICS.108.823245
PMCID: PMC2801872

Genes

MAGI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20031579-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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