Article
Genome-Wide Association Study of Peripheral Artery Disease.
Circulation. Genomic and precision medicine - 1 Oct 2021
van Zuydam Natalie R, Stiby Alexander, Abdalla Moustafa, Austin Erin, Dahlström Emma H, McLachlan Stela, Vlachopoulou Efthymia, Ahlqvist Emma, Di Liao Chen, Sandholm Niina, Forsblom Carol, Mahajan Anubha, Robertson Neil R, Rayner N William, Lindholm Eero, Sinisalo Juha, Perola Markus, Kallio Milla, Weiss Emily, Price Jackie, Paterson Andrew, Klein Barbara, Salomaa Veikko, Palmer Colin N A, Groop Per-Henrik, Groop Leif, McCarthy Mark I, de Andrade Mariza, Morris Andrew P, Hopewell Jemma C, Colhoun Helen M, Kullo Iftikhar J
Abstract excerpt
BACKGROUND: Peripheral artery disease (PAD) affects >200 million people worldwide and is associated with high mortality and morbidity. We sought to identify genomic variants associated with PAD overall and in the contexts of diabetes and smoking status. METHODS: We identified genetic variants associated with PAD and then meta-analyzed with published summary statistics from the Million Veterans Program and UK...
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