Article
Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.
BMC medical genetics - 19 Sept 2007
Levy Daniel, Larson Martin G, Benjamin Emelia J, Newton-Cheh Christopher, Wang Thomas J, Hwang Shih-Jen, Vasan Ramachandran S, Mitchell Gary F
Abstract excerpt
BACKGROUND: About one quarter of adults are hypertensive and high blood pressure carries increased risk for heart disease, stroke, kidney disease and death. Increased arterial stiffness is a key factor in the pathogenesis of systolic hypertension and cardiovascular disease. Substantial heritability of blood-pressure (BP) and arterial-stiffness suggests important genetic contributions. METHODS: In Framingham Heart...
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