Article
Association of apolipoprotein E promoter polymorphisms with bone structural traits is modified by dietary saturated fat intake - the Cardiovascular Risk in Young Finns study.
Bone - 1 May 2011
Tolonen Sanna, Mikkilä Vera, Laaksonen Marika, Sievänen Harri, Mononen Nina, Hernesniemi Jussi, Vehkalahti Kimmo, Viikari Jorma, Raitakari Olli, Kähönen Mika, Lehtimäki Terho
Abstract excerpt
Association of apolipoprotein E (APOE) ε4 allele with peripheral quantitative computed tomography (pQCT) bone traits at the distal and shaft sites of the radius and tibia was evaluated in the Young Finns Cohort (n=1777). We also analyzed the interactions of the APOE promoter polymorphisms (-219G/T rs405509 and +113G/C rs440446) and bone traits within the APOE ε3/ε3 genotype (n=1025 and n=1013, respectively), and...
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