Article
The TRAF1/C5 locus confers risk for familial and severe alopecia areata.
The British journal of dermatology - 1 Apr 2010
Redler S, Brockschmidt F F, Forstbauer L, Giehl K A, Herold C, Eigelshoven S, Hanneken S, De Weert J, Lutz G, Wolff H, Kruse R, Blaumeiser B, Böhm M, Becker T, Nöthen M M, Betz R C
Abstract excerpt
BACKGROUND: Alopecia areata (AA) is a common hair loss disorder with a complex mode of inheritance. Autoimmune mechanisms are presumed to be crucial aetiologically. It is plausible that a number of autoimmune disorders may share a common genetic background. This phenomenon has been demonstrated in previous studies, which have shown an overlap of susceptibility alleles between AA and other autoimmune disorders....
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