Article
Signal transduction in CHO cells stably transfected with domain-selective forms of murine ACE.
Biological chemistry - 1 Jan 2000
Sun Xiaoou, Rentzsch Brit, Gong Maolian, Eichhorst Jenny, Pankow Kristin, Papsdorf Gisela, Maul Björn, Bader Michael, Siems Wolf-Eberhard
Abstract excerpt
Membrane-bound human angiotensin-converting enzyme (ACE) has been reported to initiate intracellular signaling after interaction with substrates or inhibitors. Somatic ACE is known to contain two distinct, extracellular catalytic centers. We analyzed the signal transduction mechanisms in cells transfected with different forms of murine ACE (mACE) and investigated whether the two domains are similarly involved in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
