Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A mariner-based transposon system for in vivo random mutagenesis of Clostridium difficile.

Applied and environmental microbiology - 1 Feb 2010

Cartman Stephen T, Minton Nigel P

Abstract excerpt

Understanding the molecular basis of Clostridium difficile infection is a prerequisite to the development of effective countermeasures. Although there are methods for constructing gene-specific mutants of C. difficile, currently there is no effective method for generating libraries of random muta...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clostridioides difficile
Share to DNA Transposable Elements
Share to Enterocolitis, Pseudomembranous

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Library

Share to Genes, Bacterial

Share to Mutagenesis, Insertional

Share to Plasmids

Share to Transposases

Source

Open in PubMed Open full text

Identifiers

PMID: 20023081
DOI: 10.1128/AEM.02525-09
PMCID: PMC2820977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20023081-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A mariner-based transposon system for in vivo random mutagenesis of Clostridium difficile.PMID 20023081Read ↗

High-Throughput Analysis of Gene Essentiality and Sporulation in Clostridium difficileSemantic proximity Read ↗

In vivo random mutagenesis of Bacillus subtilis by use of TnYLB-1, a mariner-based transposon.Semantic proximity Read ↗

Transposon mutagenesis.Semantic proximity Read ↗

Development and Use of an Efficient System for Random <i>mariner</i> Transposon Mutagenesis To Identify Novel Genetic Determinants of Biofilm Formation in the Core <i>Enterococcus faecalis</i> GenomeSemantic proximity Read ↗

Construction and analysis of chromosomal Clostridium difficile mutants.Semantic proximity Read ↗

A Modified R-Type Bacteriocin Specifically Targeting Clostridium difficile Prevents Colonization of Mice without Affecting Gut Microbiota DiversitySemantic proximity Read ↗

Behavior and target site selection of conjugative transposon Tn916 in two different strains of toxigenic Clostridium difficile.Semantic proximity Read ↗

A toolkit for transposon libraries and functional genomics in intestinal BacteroidalesSemantic proximity Read ↗

Genome-wide transposon mutagenesis of Borrelia burgdorferi for identification of phenotypic mutants.Semantic proximity Read ↗

Transposon-mediated random mutagenesis of Bacillus subtilis.Semantic proximity Read ↗

<i>In silico</i>analysis of sequenced strains of<i><i>Clostridium difficile</i></i>reveals a related set of conjugative transposons carrying a variety of accessory genesSemantic proximity Read ↗

Theophylline-based control of repA on a Clostridioides difficile plasmid for use in allelic exchange.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.