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Article

Behavior and target site selection of conjugative transposon Tn916 in two different strains of toxigenic Clostridium difficile.

Applied and environmental microbiology - 1 Apr 2012

Mullany Peter, Williams Rachel, Langridge Gemma C, Turner Daniel J, Whalan Rachael, Clayton Chris, Lawley Trevor, Hussain Haitham, McCurrie Katherine, Morden Nicky, Allan Elaine, Roberts Adam P

Abstract excerpt

The insertion sites of the conjugative transposon Tn916 in the anaerobic pathogen Clostridium difficile were determined using Illumina Solexa high-throughput DNA sequencing of Tn916 insertion libraries in two different clinical isolates: 630ΔE, an erythromycin-sensitive derivative of 630 (ribotype 012), and the ribotype 027 isolate R20291, which was responsible for a severe outbreak of C. difficile disease. A...

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Identifiers

PMID: 22267673
DOI: 10.1128/AEM.06193-11
PMCID: PMC3302608

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Source receipt: pubmed, retrieved 7 Sept 2026.

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