Development and Use of an Efficient System for Random <i>mariner</i> Transposon Mutagenesis To Identify Novel Genetic Determinants of Biofilm Formation in the Core <i>Enterococcus faecalis</i> Genome

Abstract excerpt

Enterococcus faecalis is a gram-positive commensal bacterium of the gastrointestinal tract and an important opportunistic pathogen. Despite the increasing clinical significance of the enterococci, most of the genetic analysis of these organisms has focused on mobile genetic elements, and existing tools for manipulation and analysis of the core E. faecalis chromosome are limited. We are interested in a...

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