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Article

β-cell development and turnover during prenatal life in humans

19 Dec 2009

Abstract excerpt

INTRODUCTION: beta-cell regeneration is an area under active investigation for the future treatment of diabetes, but little is known about the patterns and dynamics of prenatal beta-cell development in humans. In particular, the quantitative changes in beta-cell mass in the developing pancreas have not been elucidated in detail. We addressed the following questions in prenatal humans: i) what is the timing of...

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PMID: 20022941
DOI: 10.1530/eje-09-1053

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